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Malaria is responsible for over 650,000 deaths annually, mainly in Africa. 3 billion, in what was the largest settlement until then between the Justice Department and a drug company. The fines stemmed from production of improperly made and adulterated drugs from 2001 to 2005 at GSK’s subsidiary, SB Pharmco Puerto Rico Inc. GSK and Pfizer to merge HIV portfolios”.

Press release: Malaria vaccine candidate reduces disease over 18 months of follow-up in late-stage study of more than 15,000 infants and young children”. 1664-1964 “The Story of a Town”, Tricentennial Committee. 2003 and filed a whistleblower lawsuit. Archived from the original on 8 June 2011.

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5 billion of products each year. 20 billion in deals, with Novartis selling its vaccine business to GSK and buying GSK’s cancer business. According to the New York Times, the case began in 2002 when GSK sent experts to fix problems cited by the FDA. Lesney, “The ghosts of pharma past”, Modern Drug Discovery, January 2004, pp.

The results of GSK’s RECORD trial were published in June 2009. There were concerns in the 2000s about the sugar and vitamin content of Ribena, a blackcurrant-based syrup and soft drink owned by GSK until 2013. For 10 years GSK marketed Paxil as non-habit forming. In 2013 the FDA rejected that the drug had caused excess heart attacks. Global alliance to eliminate Lymphatic Filariasis”.

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Acyclovir: discovery, mechanism of action, and selectivity”. Company was founded in 1880 in London by the American pharmacists Henry Wellcome and Silas Burroughs. Archived 14 October 2012 at the Wayback Machine. 3 Billion in Fraud Settlement”, The New York Times, 2 July 2012.

D in the Decade of Vaccines: breakthroughs, challenges and opportunities”. As of 2013 RTS,S, which uses GSK’s proprietary AS01 adjuvant, was being examined in a Phase 3 trial in eight African countries. Walmsley was a management professional originally from Lancashire with a background in marketing. Emma Walmsley becomes latest female CEO in FTSE 100 as she replaces Sir Andrew Witty at GSK”. 3 Billion to Resolve Fraud Allegations and Failure to Report Safety Data”, United States Department of Justice, 2 July 2012. In 1859 Beecham opened its first factory in St Helens, Lancashire.

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British pharmaceutical company headquartered in Brentford, London. Sherman Act and also seeking to have the patents declared invalid. FDA Approves Additional Vaccine for 2009 H1N1 Influenza Virus”. Glaxo’s RTS,S Malaria Vaccine Shows Promise, Scientists Say”.

Vane served as Group Research and Development Director for The Wellcome Foundation from 1973 to 1985. It was the largest health-care fraud case to date in that country and the largest settlement by a drug company. Long, “Paths to Creating Value in Pharmaceutical Mergers,” in Steven N. In 2013 GSK licensed its HIV portfolio to the Medicines Patent Pool for use in children, and agreed to negotiate a license for dolutegravir, an integrase inhibitor then in clinical development.

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In 1999 John Buse, a diabetes specialist, told medical conferences that rosiglitazone might carry an increased risk of cardiovascular problems. GSK confirms 500 mln stg UK investment plans”, Reuters, 22 March 2012. Gertrude Elion, Drug Developer, Dies at 81″. In March 2018, GSK announced that it has reached an agreement with Novartis to acquire Novartis’ 36. Clavulanic acid, a novel beta-lactamase inhibitor–a case study in drug discovery and development”.

Glaxo unit buys Breathe Right maker”. The ASA’s ruling was upheld by the High Court. 18s, although the drug had not been approved for pediatric use. Chinese authorities arrested four GSK executives as part of a four-month investigation into claims that doctors were bribed with cash and sexual favours. The settlement also covered reporting false best prices and underpaying rebates owed under the Medicaid Drug Rebate Program, and kickbacks to physicians to prescribe GSK’s drugs. 2014 into GSK’s sales practices, using powers granted by the Bribery Act 2010.

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Archived from the original on 15 April 2012. 20 Billion in Assets”, The New York Times’, 22 April 2014. Among these, albendazole, amoxicillin, amoxicillin-clavulanate, allopurinol, mercaptopurine, mupriocin, pyrimethamine, ranitidine, thioguanine, trimethoprim and zidovudine are listed on the World Health Organization’s list of essential medications. The headquarters moved from the United States to England. Glaxo Laboratories was registered as a subsidiary company in London in 1935.

The FDA placed restrictions on the drug, including adding a boxed warning, but did not withdraw it. In June 2007 the New England Journal of Medicine published a meta-analysis that associated the drug with an increased risk of heart attack. Beechams, 1848-2000: from Pills to Pharmaceuticals. The Wellcome Tropical Research Laboratories opened in 1902. Black “”for their discoveries of important principles for drug treatment”.

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Glaxo Files Its Entry in Race for a Malaria Vaccine”. D centre in China in 2007, in Shanghai, initially focused on neurodegenerative diseases. Horlicks, Boost and a chocolate-flavoured malt drink sold in India.

Philip Hampton, at that time chair of the Royal Bank of Scotland, became GSK chairman in September 2015. Mergers and Productivity, University of Chicago Press, 2000. Partners resolve their differences and unite at the second attempt”.

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Davenport-Hines, Judy Slinn, Glaxo: A History to 1962, Cambridge University Press, 1992, pp. Smith opened his first pharmacy in Philadelphia in 1830. 3bn after bribing doctors to increase drugs sales”, The Guardian, 3 July 2012.

In 1983 the American arm, Glaxo Inc. John Vane of Wellcome Research Laboratories shared the 1982 Nobel Prize for Medicine for his work on prostaglandin biology and the discovery of prostacyclin. In 2009 the company said it would cut drug prices by 25 percent in 50 of the poorest nations, release intellectual property rights for substances and processes relevant to neglected disease into a patent pool to encourage new drug development, and invest 20 percent of profits from the least-developed countries in medical infrastructure for those countries.

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10,000 face Glaxo’s axe at Wellcome”. The World’s Biggest Public Companies”, 2015 ranking, Forbes. GSK sells BC, Goody’s and other brands”. The government appealed to the Supreme Court, which reversed, in United States v.

GSK threatened to sue him, called his university head of department, and persuaded him to sign a retraction. The case revolved around intracompany transfer pricing—determining the share of profit attributable to the US subsidiaries of GSK and subject to tax by the IRS. US headquarters until the company moved to Research Triangle Park in North Carolina in 1971. The effect and intent of the bulk-sale restriction was to keep the drug chemical out of the hands of small companies that might act as price-cutters, and the effect was to maintain stable, uniform prices.

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A review of its antibacterial activity, pharmacokinetic properties and therapeutic use”. 2003 GSK had formed another subsidiary, GSK Ventures, to out-license or start new companies around drug candidates that it did not intend to develop further. Chris Gent, previously CEO of Vodafone, was appointed chairman of the board in 2005. David Newton, Trademarked: A History of Well-Known Brands, from Airtex to Wright’s Coal Tar, The History Press, 2012, p. A company poster showed bottles of Toothkind in place of the bristles on a toothbrush. James Quinn, “Sir Philip Hampton to chair Glaxo”, The Daily Telegraph, 25 September 2014.

As of 2003, SR One tended to invest only if the company aligned with GSK’s business. Is Corporate Venture Capital a Prescription for Success in the Pharmaceutical Industry? 1873 as a general trading company in Wellington, New Zealand, by a Londoner, Joseph Edward Nathan.